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ACCEPTING PHD STUDENTS
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Assistant Professor Dennis Kappei
status-symbol ACCEPTING PHD STUDENTS
Faculty & Department
Biochemistry
Joint Appointments

Jt Appt - Assistant Professor, Research, Cancer Science Institute of Singapore

Education

Doctor of Philosophy, Dresden University of Technology, Germany

Contact Information
email-icondennis.kappei@nus.edu.sg
Kappei Lab Website @CSI
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Telomere
Cancer Biology
Chromatin Organization And Dynamics
Epigenetics
Gene Expression
Genome Instability
Mass Spectrometry
Proteomics

Our research group is interested in how telomere-driven genomic instability contributes to carcinogenesis. For this purpose, we leverage our strength in quantitative mass spectrometry analysis to both identify novel, direct telomere-binding proteins as well as to study changes in telomeric chromatin composition upon genetic manipulation. For the latter we have established workflows for label-free quantitative proteomics analysis in combination with chromatin immunoprecipitation (qChIP-MS) and extended this work to locus-specific purification workflows. Since many telomeric proteins moonlight as transcription factors, we further study the mechanism and functional impact of their gene regulatory roles both as a feedback loop with telomeres as well as to carefully dissect separation of function.

My Mentoring Style

How would you describe your mentoring style in terms of freedom given to your students?

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Autonomy
Adaptive
Mentorship

Selecting Research Topics?

How do you guide your PhD students in selecting research topics?

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Curated
Align
Collaborate
Student-led

Setbacks / Challenges

How do you handle setbacks or challenges faced by your PhD students?

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Independent
Nudge
Guidance

Feedback

How do you give feedback on your students’ thesis drafts and progress?

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Minimal
Brief
Detailed

Consultation Frequency

How often do you typically meet your PhD students one-on-one for consultation?

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Weekly
Bi-Weekly
Monthly
As Needed

Research Group Meetings

How often do you typically hold lab meetings where your PhD students present their research work to the class?

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Weekly
Bi-Weekly
Monthly
As Needed
Contact Information
email-icondennis.kappei@nus.edu.sg
Kappei Lab Website @CSI
open-newLinkedIn