There are simply too many challenges I came across during graduate studies and I really do not know where to start with. It has been a bittersweet experience mixed with excitement, sense of fulfillment, self-doubt and pains. Basically, most of the frustration and stress came when you were about to approach certain deadlines or clinching for certain key goals, yet the experimental results would not agree with your own hypotheses. Sometimes, after some painstaking periods of extra works, you eventually got what you were asking for. Yet, most of the time, your tries simply kept failing and you just had to admit it and change direction as fast as you could, while pulling yourself together and learning how to report these ‘disappointing’ results professionally to your advisor. This process is absolutely much harder than it sounds as it touches on many soft parts of a grown man/woman, including ego, pride, self-recognition, etc., and it can easily demoralize someone so much so that he/she could simply give up on this journey. For a graduate student to finally call himself/herself a qualified scholar, he/she has to firstly master how to gracefully anticipate and confront failures.