Wen Shan YEW is Associate Professor and Head of the Department of Biochemistry at the Yong Loo Lin School of Medicine at the National University of Singapore. His other academic appointments include Assistant Dean (Graduate Studies), Deputy Director of the NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Deputy Director and Research Director of the Synthetic Biology Translational Research Programme, and Director of the HH@NUS SINERGY Laboratory. He is the current President of the Singapore Society for Biochemistry and Molecular Biology, and a Council Member of the Singapore National Academy of Science. He trained as a mechanistic enzymologist with Professor John A. Gerlt from the University of Illinois at Urbana-Champaign. His current and future research is centered on expanding the multi-faceted interface between enzymology, biological chemistry and synthetic biology, in an area he terms “synthetic enzymology”. In particular, his research is focused on the use of structural and mechanistic enzymological knowledge for protein engineering (exploring, defining and modulating substrate specificities), biocatalysis, biotransformation, therapeutic development (against metabolic diseases, infectious diseases, cancer and ageing) and bioremediation (towards urban sustainability). His research is closely aligned with industrial needs and solutions, and he is currently part of the Wilmar@NUS Corporate Laboratory, the HH@NUS SINERGY Laboratory, the Centre for Precision Fermentation and Sustainability (PreFerS), the National Centre for Engineering Biology of Singapore, and the Bezos Centre for Sustainable Protein. He is the Lead PI for the Singapore International Spoke of the Bezos Centre for Sustainable Protein.