Assoc Professor Lih Wen Deng
Associate Professor, Integrative Sciences and Engineering
Doctor of Philosophy, University of Cambridge, United Kingdom
Bachelor of Science in Agriculture, National Taiwan Univ, Taiwan
Dr. Lih-Wen Deng is an Associate Professor in the Department of Biochemistry at the National University of Singapore (NUS). She received her Ph.D. from the University of Cambridge and completed her postdoctoral studies at Harvard University. Her research focuses on the molecular mechanisms of cancer development, particularly in therapy resistance and metastasis. Her recent work includes identifying cancer-testis antigens regulating chromatin dynamics in radioresistance and exploring cysteine metabolism in ovarian cancer. She collaborates with clinicians to develop prognostic markers and therapeutic strategies. She is also an affiliated member of NUS Center for Cancer Research and the National Cancer Institute Singapore.
My lab is interested in understanding the cellular and molecular mechanism in cancer development and developing novel targets for therapeutic cancer intervention. Current research areas include: 1) Genomic instability and chromatin dynamics in cancer development; 2) Mechanisms of therapy resistance; 3) Therapeutic potential of targeting cancer metabolism and tumor microenvironment; 4) Cancer oxidative stress and glutathione homeostasis