Main Menu

N2CR Graduate Student, Viresh Krishnan Sukumar, publishes in Cancers on 'magnetic therapy improving breast cancer treatment'.

About the Publication

Journal Article

Chemotherapy, although the first line of defense in cancer treatment, is indiscriminate and is damaging to the entire body, which, ironically, worsens a patient’s chances of getting better from cancer. Doxorubicin is a widely used chemotherapy drug for breast cancer but has significant side effects due to its systemic delivery. This study led by co-first authors, Viresh Krishnan Sukumar (N2CR PhD Scholarship student) and Dr Alex Tai Yee Kit, found that a 10-minute magnetic exposure increases doxorubicin uptake in breast cancer cells without harming the surrounding healthy cells. The study suggests a localized, non-invasive magnetic therapy to enhance doxorubicin efficacy with fewer side effects. This may ultimately allow for the lowering of systemic doxorubicin administration that could improve a patient’s outcome against cancer. This would be a potential game changer in cancer treatment.

Featured Author

Mr. Viresh Krishnan Sukumar
Mr. Viresh Krishnan Sukumar

Surgery

PhD Student

Thesis Advisor

Associate Professor Alfredo Franco-Obregon

Publication Details

Publication Title
Brief Magnetic Field Exposure Stimulates Doxorubicin Uptake into Breast Cancer Cells in Association with TRPC1 Expression: A Precision Oncology Methodology to Enhance Chemotherapeutic Outcome
Publisher
Cancers
Year
2024
DOI
10.3390/cancers16223860
Publication Link
https://www.mdpi.com/2072-6694/16/22/3860

Posted By

Medicine ( afo@nus.edu.sg ) — Thesis Advisor